Indianapolis Colts at New England Patriots: Predictions, picks and odds for NFL Week 13 game

Indianapolis Colts at New England Patriots: Predictions, picks and odds for NFL Week 13 game

November 27, 2024

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Neither Tom Brady nor Peyton Manning will be suiting up for when the Indianapolis Colts (5-7) visit the New England Patriots (3-9), but they do have young quarterbacks hoping to one day live up to the legacy.

Good news for Indianapolis: the Detroit Lions didn’t have a lights-out scoring day against them. The bad news? its own offense couldn’t do anything in a 24-6 defeat. The season has been full of ups and downs, but the Colts still have a chance to finish strong, making them an interesting team to watch.

Right now is not a good time to face the Miami Dolphins, and New England learned the hard way with a loss against a divisional foe that wasn’t as close as the score indicated. It’s safe to say the Patriots aren’t going anywhere this season, but the fanbase would love to see Drake Maye show progress and grab some wins.

Patriots vs. Colts odds, moneyline, over/under

The Colts are favorites to defeat the Patriots, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week.

  • Spread: Colts (-2.5)
  • Moneyline: Colts (-150); Patriots (+125)
  • Over/under: 42.5

NFL Week 13 odds, predictions and picks

Lions vs. Bears | Cowboys vs. Giants | Packers vs. Dolphins | Chiefs vs. Raiders | Falcons vs. Chargers | Bengals vs. Steelers | Jaguars vs. Texans | Vikings vs. Cardinals | Patriots vs. Colts | Jets vs. Seahawks | Commanders vs. Titans | Panthers vs. Buccaneers | Saints vs. Rams | Ravens vs. Eagles | Bills vs. 49ers | Broncos vs. Browns

Lorenzo Reyes: Colts 26, Patriots 17

Indianapolis struggled against the Lions, but that shouldn’t be too much of a knock on the Colts; Detroit is an elite contender. The Patriots are still finding their way with Drake Maye running the offense. I like the Colts in a bounce-back here, with Anthony Richardson giving New England’s defense fits.

Tyler Dragon: Colts 20, Patriots 19

This game features two young promising quarterbacks, but the Colts have a better roster around Anthony Richardson. Indy is in the playoff mix and needs a win to remain in the hunt. 

Richard Morin: Colts 24, Patriots 22

Look, rookie Drake Maye has a ton of promise. But the Patriots have a laundry list of roster issues. Their offensive line has been terrible, their defense is wildly inconsistent and they appear to be poorly coached. Maye has very few reliable options on offense. I don’t love any play here, but I feel cautiously optimistic about a Colts win.

Jordan Mendoza: Colts 16, Patriots 13

The New England offense has been struggling, but the defense should be able to limit Indianapolis from having a solid game. Still, Anthony Richardson finds a way to get a late score. A good candidate to bet the under.